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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cf00525b37f3ba7d6e54ed1d313836c1ec936ad55dab674d28248a7596d5da' 
  AND token = 'd9JR6Rpr3PZyFbE2X/yC07G8AGz5FSfY5iFbfJjlMII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}