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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1fe3a05409847fdc559792ad57871807d0a3064ccbc5e80b1df223df727cea' 
  AND token = '+sF3M40XVgGYezVs1uaz8vbAOHVb5vyGUoILcc03nCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}