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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd791059f59850be87ef5a0386cd119526a665dd35f013d2a49fa6c04faeb21' 
  AND token = '2Y/6edmjcq0CLv2a5Qe8sbG8aJCMgAlRhjK7wz9bIQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}