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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d3f933c7c9a463089b1d8bf3996a370bc29fbe0559057da9e8e6e51927c971' 
  AND token = 'fYvNSRP6nDt1shEO+M7aX78ukHA/U649ThyltG90diY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}