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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5101513712af911f365d388f4faf5989b1c6d451b0fddf897f64483f7859dbe4' 
  AND token = 'ozr9IILG7uW8jy1+bGeGISz8L3MDVqzEbvoyY+kN/oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}