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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c90e59d71fef556236ecbbe00d4a955cb1e4c5d46050017dcde3de79c2e95134' 
  AND token = 'toLnI8m/UBlc0B9n6qAgU/ulO6j+6dxPi5iAFgxeZ+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}