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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f15e7a01a76df1569a08ae91f6c1ebd16741525c4d25c88b9f12505a0414947' 
  AND token = '+nlie64CjcKqbZuDBla67zDff48eGCx0s6byGpPgRCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}