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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cff246a979f4666212c9857a91b5ddb07fd573e11125f146c90133394d3ab5b' 
  AND token = '4KkoItT6tO99A2Uyu1oEw4wa/3DPuTXnahO/ToQyw6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}