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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2d2a8e240bcaddc7a21e106abff6a78ec6065b98c461b49cd8a8c1e8af0bd7' 
  AND token = 'pZgv4BOinbb24GDBDuYVBCN1Q2zWkOuTY+zv9guAfyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}