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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de6c62325bc3c2794326e32bb5cd1c349790fc674bf6c6b595b89482e834a81' 
  AND token = 'pFlqrOt7x5teVe9h/2NWH7qOZA+mtD8MA9ep0/YMajU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}