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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c588f6dff8482066fd722cd24b6fea3ced32cb4dd6fa8ca0535b0518fce6d2fb' 
  AND token = '7lpIKiPjwIE6Z9yonPOPFUbJ1F1gCZE40DaF9UMDhcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}