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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce42bb7d5540fd74167f5667d087f4ddf54e6571b74970ab72c365c84f0355bd' 
  AND token = '4iEgUlZoQuKBChZ6raxy1AarLoPIKrcIT7TyTpF4+m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}