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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e6a16d248605950c293b89422c80cee9361ec9bd4d8a8fc59c8c2b0d1607e7' 
  AND token = 'JmePPrAQFYW6IndbkoPiF337+l6edX5HCdsxyFDmTs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}