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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d721a60e8d0b9acbca290f9793fe175e8b86cab66e67a846a116508639a3b01' 
  AND token = 'S3aTVIp622F9AvTLMCAxZy4ElR4oCYQdcC7BQlfL5YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}