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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f74ad36c8c80f507c9bcaa78be6f9ef079dcc06338ed3c99a7cd6b9669a854d' 
  AND token = '0H6LF0QdCC1TGgdc5jWfdOkGMghVj+yGp8GYCY0Tt+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}