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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6dd9aa613ec938b7c757347c0ec89d1281e4d271d8c21065ed694309a9edd56' 
  AND token = 'S1iv6IeNAuGeajsagmujcQUjD3+8TNdJNOOrronGQ5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}