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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004d354813537ea147e53f36061387b6865b879202d99e735ff1fcaec9e395c3' 
  AND token = '5doZTw0OQQWARnat2/ZdbMjx6xzslDfugu9eevPFBLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}