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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28453927aeb6f9f5eacc1a66f15597b8fc55bacadf02c8c62249a2190da10d7b' 
  AND token = '7N+z5wZlV6LfDSS1/becNHRJFPBWvS3wr5KIRHCk4dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}