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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2508f376c5e7d83ad5fae1debcec45342aed4d8b1dac00fc65976529677461b5' 
  AND token = 'OgEK1EFwEgt6lv5G7pln2DBA0FWKD9qLAkpKAhGoCXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}