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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546436e2c14bc1f8927c6d18cbca9867d5333ec0b629b91811a5841011a0db99' 
  AND token = 'khQxSlowkE05Qw/Us85RPdCR7mzT2eyeSSQiB3l7e0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}