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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6600fcb96e2291e9d8dc387336f9def98e3e68936807e8411bf262883c56c96' 
  AND token = 'NEkkFE0+G9VRfSAenid9hW0C6dxnsPdKjLJ401UMZ8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}