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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '252b5f123fe6adc2854b0f745e1db3e627e31edfd7cba6eddbeef9507c09b65e' 
  AND token = 'AjSc6L9OH59s5pQXY5gwaaUHQFXQbeygUCM3YWXl7cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}