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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8285171841ac2afa5eb8012530721cbee8b95fb70b8d36b74284a92d5bf1c71' 
  AND token = 'S6PQsTajJxilriwmhbfwjrE3O77eY+4Ob7m1PTEL20c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}