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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cda20f86ac5c8d4fc5849f37d591cfc1b1f3ec05a698dfed909a266941e1a17' 
  AND token = '2IBP9zMl/+x+DXrphgNj0nP9Zazds68uU3abGhTx3OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}