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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ddf93de5b12e17b275af30a40270256fe5b46b637293a05e918b624b0eb4662' 
  AND token = 'k+VAYzdxylY2l2Fz4UXyl1w/6wH4RnG5J+XpXHiaLd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}