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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f3535f353cc8157ed299b09d5f564bc0ee442fc77629302e2a62e0d36c2c3a' 
  AND token = 'TOqWcpbn5oTgxwpcTJQAZXXifLq63HkhUCKyNwDd398=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}