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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e614c89b55111d671a7dcc950e2c245cf835de62b03d4450bdb22741bf2e45' 
  AND token = '6c3B8+U7ZrcJZqYlKAhh4D5CB1vZNsxXHjoIH3wB4ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}