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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1cb5d012b07d4307b4460262a4cb036505ac76cc74e852934b9f09b82863814' 
  AND token = 'zC7m50n3g7Yw7wmngsgv0rHdeWj2qnl+c63AmbJ37Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}