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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f94acb8b3b12c50818d665d2001114007b1ff492ff33f1c0b328555e7f41195' 
  AND token = 'mkDKy+gvUYMFNTyS1PQ4S8YXj0v412eU7+32jZj2gOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}