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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6bedf350f8235b12f8558a1ed10b309ac91877db48b8acdd2bb66451fc6383' 
  AND token = 'jhbWyIgT9yE6KZ3RiMnwDT3LsIONy4wAgyjZ+PNMFoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}