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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb6cec956c62e72ec7344065762d3a839dcc7a121a31c58a67d36f5a79a8c80' 
  AND token = 'cSJR1PYpsKlCTYVLO2kr5PWGi/hSScDl8nhwRQfqDnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}