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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044afe6b85832d3a38a55b3546c57f76f01a440aead172693e36456437ff47bd' 
  AND token = 'cfaGnLfxbzmxaOMdPL5Vm/q9cMyDLsDfGN3vdKOL5z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}