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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15485d117eddd8fb274e7c5c3be5425bf331cf7e41914e0f7c8ba4cacc56ffeb' 
  AND token = 'Jbj2l0bDHMiBkvL84GSqqlGnbjrV/HoP8cPaq6pJZn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}