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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e577fc8c991ca0569f68656198051a148c0aa91d5673e0f217bb113d00cf4e3b' 
  AND token = 'lrSR3UYJ66CsihZ61MM1HhyB09C9n0JW8njlHtQ5nK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}