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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace0d4fab6aa7d7e8906050389939d782139fc1c47b72793c1f1f143b003d6c4' 
  AND token = 'waU54l0u9kvbU4rdTibAW6vkQu3UqW2acCXTzoXoc0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}