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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4957ca8ba11c3b43ada40f064b7bd20cfce696eb963374d6f486b7054ff4b6c3' 
  AND token = 'ziu5fSd0Wt3IGdsaAvdGHsFmniiBKyInKuj+jZEz2s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}