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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae7c1744a96cc5a6721ea8e7331a97ed3a0b220be818e347b2521be2b67ead5d' 
  AND token = 'PF9wz1XJXTakM7rqMM9d7xz5503EcCieHSknrLM1sTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}