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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32d18ffa5e64a8f6509b47de426134d114d850d2546d09d49a8b6f0e5d8269ee' 
  AND token = '+JyY+GgS6Y2aF/oJitiCWBpYc0bzKKzKz2sxLfPMehE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}