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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4404118a8cb534ed4b1bf80275176e78aeae3a775ab84c93bb8654a4ae48b18b' 
  AND token = 'Z5kj/niaSCYufL/YPYCUwcV5yP0+W81zAs1sWRyVxAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}