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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e377c59d840b636e78017afda94aa48bf3065496510e8d4bc38a9876a256b2a' 
  AND token = '2pdPIPdHfa5xQp3+5Hn69OOdiMt3c+sLlmDSlprMbg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}