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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce63114810066ede1bc1a2ade4c610eca1c5250c8d2d0017abcb4b3b01b85408' 
  AND token = '/DoFzcNpwW4gmdNHZmMKl1jr7bT1Y0QgBI2qCVQ/BEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}