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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8be3f3d7e1970f871a713fe7d1b78292e5b3e9e832d1b7509400c7c6e42cd53' 
  AND token = 'cuga9BN9t6QVfr48BFfWhW4Z3dHC8ow4hg02k+fxBvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}