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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ead0f65c49658c47b0b2e72e49db45f6cc8564ee822a975c9052cdd9eae4a62' 
  AND token = 'OLKfuCOIrG/AoN6ZFB/QdCKp3wwRIDTQnTPM6YdflWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}