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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67440b1a86ad780a41b8b6e35a4432f42c55326918f92e41f6a879367d6f920f' 
  AND token = 'ttXdcVGrvGuIJHugPeq3TMk87bG5AMIcGxiFd2907iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}