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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f6464bee13df364c7631ef527d0b815d057183bcb20d711a5b5b99014cbf32' 
  AND token = 'iC5XNkJ1AmooNWGdldMGKNPBgTvM/A9ONiOXsi1a6oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}