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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a83c5e54030c804d803ceecb3040dd1ce01f6675d8959a840fae00d7c241552' 
  AND token = 'GYXyJFPyggSLbNUqNNAOzF1k68xTryZK9Hx8j24pjO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}