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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c357fd5b81c479bff2e47f7840ebd71357bb3bbb63c77f638e144d60ff06055' 
  AND token = 'KfKH1x22eJ0wcE8rSu+haFA/hKl23OHmQCCYmpzHwMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}