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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa5acd054339783d9fbf3d508571411a29d540225e92059896063e2900c6b1de' 
  AND token = 'NszBJrZbrs3MT2twuWr2aTI0y/sdn94N8IFfteT4Ml8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}