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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd69c7760bca473c6d2eda9106255a621a7c1d1447d900fa92202a2e04d73f402' 
  AND token = 'fUA7smo4X1aCs7Muu4pum0gyFFqAvW/kHgO1S4ANhKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}