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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b44bf40c4d20f916df36441163499b1a9f35bb429d921048abf49b6998f3c1c2' 
  AND token = '00oFfKJgHzd5NQM9z59Rea11oCxemZqtbU51qCrNkJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}